One man was arrested and cannabis seized after police stopped a car in the Coalisland area.
A search was carried out on both the car and the four men.
Two of the men were dealt with for possession of a Class B drug.
Police want the public to be vigilant and to report any concerns or suspicious activity.
Vaccination appeal amid ‘very concerning’ increase in flu cases
Police probe report of shot fired at a house in Newry
MLAs clash with officials over Bill to make school uniforms more affordable
Further bluetongue testing after 44 more suspected cases found