Rory Best will be on the bench for the Friday night game at Scotstoun
Fullback Jared Payne and back row Iain Henderson return to Ulster's starting line-up for tomorrow night's Pro12 clash with Glasgow Warriors.
There are nine changes to the squad in total, including Darren Cave returning to centre, Franco van der Merwe joining Alan O'Connor in the second row and Rory Best in the replacements.
Les Kiss' men are hoping to make it four from four this competitive season, at a ground which hasn't been kind to them in recent years.
Speaking to Q Radio Sport, injured joint-captain Andrew Trimble says their opponents have a wealth of quality players.
Kick-off is at 7:35pm.
(15-9): J Payne, L Ludik, D Cave, S McCloskey, C Piutau; P Jackson, R Pienaar
(1-8): A Warwick, R Herring (captain), R Ah You, A O'Connor, F van der Merwe, I Henderson, S Reidy, R Wilson
Replacements (16-23): R Best, C Black, R Kane, P Browne, C Ross, P Marshall, S Olding, R Lyttle.