The crash happened on Sunday night on the Beltany Road between Omagh and Newtonstewart. Diversions had been in place from around ten o'clock before the road was re-opened in the early hours of this morning. All four casualties had to be treated for non-life threatening injuries.
The Beltany Road between Omagh and Newtonstewart had to be closed for nearly eight hours.
Traffic travelling on the A5 were directed along alternative routes after diversions were placed at the junction with Moyle Road and Mountjoy Road and Gortnagarn Road.
That's after two cars travelling on the well-used section of road collided just after ten o'clock on Sunday night.
Four people, two from each car, had to be treated for non-life threatening injuries - there were no fatalities.
The Beltany Road re-opened just after six o'clock on Monday morning.
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